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MAC1
CAS No. 325970-42-1
MAC1( Monastrol Antagonizing Compound 1 )
Catalog No. M14057 CAS No. 325970-42-1
MAC1 (Monastrol Antagonizing Compound 1) is a small molecule that can rescue spindle bipolarity in cells lacking Eg5 activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameMAC1
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NoteResearch use only, not for human use.
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Brief DescriptionMAC1 (Monastrol Antagonizing Compound 1) is a small molecule that can rescue spindle bipolarity in cells lacking Eg5 activity.
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DescriptionMAC1 (Monastrol Antagonizing Compound 1) is a small molecule that can rescue spindle bipolarity in cells lacking Eg5 activity; induces the formation of additional microtubule nucleation centers, which allows kinesin Kif15-dependent bipolar spindle assembly in the absence of Eg5 activity.
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In Vitro——
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In Vivo——
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SynonymsMonastrol Antagonizing Compound 1
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PathwayCytoskeleton/Cell Adhesion Molecules
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TargetKinesin
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RecptorKinesin
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Research Area——
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Indication——
Chemical Information
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CAS Number325970-42-1
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Formula Weight247.338
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Molecular FormulaC15H21NO2
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name(E)-1-(1-hydroxycyclohexyl)-3-phenylpropan-1-one oxime
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Al-Obaidi N, et al. ACS Chem Biol. 2016 Jun 17;11(6):1544-51.
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