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Chloral hydrate
CAS No. 302-17-0
Chloral hydrate( NSC 3210 )
Catalog No. M13945 CAS No. 302-17-0
Chloral Hydrate is a synthetic monohydrate of chloral with sedative, hypnotic, and anticonvulsive properties.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameChloral hydrate
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NoteResearch use only, not for human use.
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Brief DescriptionChloral Hydrate is a synthetic monohydrate of chloral with sedative, hypnotic, and anticonvulsive properties.
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DescriptionChloral Hydrate is a synthetic monohydrate of chloral with sedative, hypnotic, and anticonvulsive properties. Chloral hydrate is converted to the active compound trichloroethanol by hepatic alcohol dehydrogenase. The agent interacts with various neurotransmitter-operated ion channels, thereby enhancing gamma-aminobutyric acid (GABA)-A receptor mediated chloride currents and inhibiting amino acid receptor-activated ion currents. In addition, chloral hydrate enhances the agonistic effects of glycine receptors, inhibits AMPA-induced calcium influx in cortical neurons, and facilitates 5-HT 3 receptor-mediated currents in ganglionic neurons. Overall, this results in a depressive effect on the central nervous system.
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In Vitro——
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In Vivo——
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SynonymsNSC 3210
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PathwayMembrane Transporter/Ion Channel
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TargetGAT
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RecptorGABAR
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Research Area——
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Indication——
Chemical Information
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CAS Number302-17-0
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Formula Weight165.4
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Molecular FormulaC2H3Cl3O2
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Purity>98% (HPLC)
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SolubilityDMSO: 10 mM
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SMILESOC(O)C(Cl)(Cl)Cl
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Chemical Name2,2,2-Trichloroethane-1,1-diol
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Delgado J, et al. Pediatr Radiol. 2015 Jan;45(1):108-14
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