NBD-14107

CAS No. 2086328-94-9

NBD-14107( NBD14107 )

Catalog No. M13251 CAS No. 2086328-94-9

A potent HIV-1 entry inhibitor that blocks the gp120-CD4 interaction.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    NBD-14107
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent HIV-1 entry inhibitor that blocks the gp120-CD4 interaction.
  • Description
    A potent HIV-1 entry inhibitor that blocks the gp120-CD4 interaction; exhibits antiviral activity against a large panel of HIV-1 Env-pseudotyped viruses representing diverse subtypes of clinical isolates with mean EC50 of 0.49 uM; also inhibits HIV-1 RT with IC50 of 8.4 uM; exhibits improving the potency, toxicity, and ADMET profile compared with NBD-14010.HIV Preclinical.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    NBD14107
  • Pathway
    Microbiology/Virology
  • Target
    HIV
  • Recptor
    HIV
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2086328-94-9
  • Formula Weight
    412.84
  • Molecular Formula
    C17H15ClF2N4O2S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    N-(2-amino-1-(5-(hydroxymethyl)thiazol-2-yl)ethyl)-5-(4-chloro-3,5-difluorophenyl)-1H-pyrrole-2-carboxamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Curreli F, et al. J Med Chem. 2017 Apr 13;60(7):3124-3153.
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