KUNG29

CAS No. 1887032-92-9

KUNG29( KUNG-29 | KUNG 29 )

Catalog No. M12952 CAS No. 1887032-92-9

A potent, selective Grp94 inhibitor with Kd of 0.2 uM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 963 Get Quote
50MG 1962 Get Quote
100MG 2520 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    KUNG29
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent, selective Grp94 inhibitor with Kd of 0.2 uM.
  • Description
    A potent, selective Grp94 inhibitor with Kd of 0.2 uM; displays 40-fold selecticity over Hsp90α; induces the degradation of integrin α2 in MDA-MB-231 cells.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    KUNG-29 | KUNG 29
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    HSP
  • Recptor
    HSP
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1887032-92-9
  • Formula Weight
    430.89
  • Molecular Formula
    C22H23ClN2O5
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(OC)C1=C(O)C=C(O)C(Cl)=C1CCC2=NC=CN2CC3=CC=CC=C3OCC
  • Chemical Name
    Methyl 3-Chloro-2-(2-(1-(2-ethoxybenzyl)-1H-imidazol-2-yl)-ethyl)-4,6-dihydroxybenzoate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Crowley VM, et al. J Med Chem. 2016 Apr 14;59(7):3471-88.
molnova catalog
related products
  • Teprenone

    Teprenone is a anti-ulcer drug and works as an inducer of heat shock proteins (HSPs).

  • 2',4'-DIHYDROXYCHALC...

    2',4'-Dihydroxychalcone as a compound with Hsp90 inhibitory and antifungal effectsIn the presence of 2',4'-DHC (8 g/mL), radial growth of Aspergillus fumigatus was inhibited 20% compared to the control, and green pigmentation was completely blocked.

  • HS-72

    HS-72 is an allosteric, selective, cell-permeable inhibitor of inducible Hsp70 (Hsp70i or Hsp72).