MZ-242

CAS No. 1862238-01-4

MZ-242( MZ242 | MZ242 )

Catalog No. M12877 CAS No. 1862238-01-4

A novel potent, selective Sirt2 inhibitor with IC50 of 0.118 uM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    MZ-242
  • Note
    Research use only, not for human use.
  • Brief Description
    A novel potent, selective Sirt2 inhibitor with IC50 of 0.118 uM.
  • Description
    A novel potent, selective Sirt2 inhibitor with IC50 of 0.118 uM; displays no inhibitory activity against Sirt1 and Sirt 3 (IC50>100 uM).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    MZ242 | MZ242
  • Pathway
    Chromatin/Epigenetic
  • Target
    Sirtuin
  • Recptor
    Sirtuin
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1862238-01-4
  • Formula Weight
    525.646
  • Molecular Formula
    C24H27N7O3S2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(NC1=NC=C(CC2=CC=CC(OCC3=CN(CCOC)N=N3)=C2)S1)CSC4=NC(C)=CC(C)=N4
  • Chemical Name
    2-((4,6-dimethylpyrimidin-2-yl)thio)-N-(5-(3-((1-(2-methoxyethyl)-1H-1,2,3-triazol-4-yl)methoxy)benzyl)thiazol-2-yl)acetamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Szabó A, et al. Sci Rep. 2017 Dec 6;7(1):17070. 2. Schiedel M, et al. Angew Chem Int Ed Engl. 2016 Feb 5;55(6):2252-6.
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