Cart
sales@molnova.com
Home - Products - JAK/STAT Signaling - STAT - BP-5-087

BP-5-087

CAS No. 1803281-30-2

BP-5-087( BP 5-087 )

Catalog No. M12758 CAS No. 1803281-30-2

A potent, selective STAT3 SH2 domain inhibitor (EC50=5.6 uM) that reduces STAT3 phosphorylation and nuclear transactivation.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 963 Get Quote
50MG 1962 Get Quote
100MG 2520 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    BP-5-087
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent, selective STAT3 SH2 domain inhibitor (EC50=5.6 uM) that reduces STAT3 phosphorylation and nuclear transactivation.
  • Description
    A potent, selective STAT3 SH2 domain inhibitor (EC50=5.6 uM) that reduces STAT3 phosphorylation and nuclear transactivation; restores TKI sensitivity to therapy-resistant CML progenitor cells in primary cells from CML patients with BCR-ABL1 kinase-independent TKI resistance, including leukemic stem cells.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    BP 5-087
  • Pathway
    JAK/STAT Signaling
  • Target
    STAT
  • Recptor
    STAT
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1803281-30-2
  • Formula Weight
    770.691
  • Molecular Formula
    C36H30F8N2O6S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    FC(F)(F)C1=CC=C(S(=O)(N(CC(N(C2=CC=C(C(O)=O)C(O)=C2)CC3=CC=C(C4CCCCC4)C=C3)=O)CC5=C(C)C=CC=C5)=O)C=C1
  • Chemical Name
    4-(N-(4-cyclohexylbenzyl)-2-((N-((perfluorophenyl)methyl)-4-(trifluoromethyl)phenyl)sulfonamido)acetamido)-2-hydroxybenzoic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Eiring AM, et al. Leukemia. 2015 Mar;29(3):586-597. 2. Eiring AM, et al. Leuk Suppl. 2014 Dec;3(Suppl 1):S5-6.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Palivizumab

    Palivizumab (MEDI 493) is a humanized RSV-specific monoclonal antibody that selectively inhibits epitopes at the F protein A antigenic site of RSV subtypes A and B for the prevention of respiratory syncytial virus infection (RSV).

  • KI16

    KI16 is a novel small molecules that inhibit STAT3-dependent transcription and function.

  • Artesunate

    Artesunate is a part of the artemisinin group of agents with an IC50 of < 5 μM for small cell lung carcinoma cell line H69.

Sign In Join Free