Cart
sales@molnova.com
Pomstafib-2
CAS No. ——
Pomstafib-2( Pomstafib 2 )
Catalog No. M17027 CAS No. ——
The pivaloyloxymethyl ester prodrug of Stafib-2, which is a potent, selective STAT5b inhibitor with Ki of 9 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NamePomstafib-2
-
NoteResearch use only, not for human use.
-
Brief DescriptionThe pivaloyloxymethyl ester prodrug of Stafib-2, which is a potent, selective STAT5b inhibitor with Ki of 9 nM.
-
DescriptionThe pivaloyloxymethyl ester prodrug of Stafib-2, which is a potent, selective STAT5b inhibitor with Ki of 9 nM; decreases the phosphorylation at STAT5b Tyr699 with IC50 of 1.5 uM in STAT5b-GFP-transfected K562 cells in human leukaemia cells and induces apoptosis in a STAT5-dependent manner; shows high selectivity for STAT5b over STAT5a.
-
In Vitro——
-
In Vivo——
-
SynonymsPomstafib 2
-
PathwayJAK/STAT Signaling
-
TargetSTAT
-
RecptorSTAT
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number——
-
Formula Weight1101.042
-
Molecular FormulaC52H66N2O20P2
-
Purity>98% (HPLC)
-
Solubility——
-
SMILES——
-
Chemical Name((((4-((2-(4-((4-phenoxyphenyl)carbamoyl)phenoxy)acetamido)methyl)-1,2-phenylene)bis(oxy))bis(oxo-l5-phosphanetriyl))tetrakis(oxy))tetrakis(methylene) tetrakis(2,2-dimethylpropanoate)
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Elumalai N, et al. Sci Rep. 2017 Apr 11;7(1):819.
molnova catalog
related products
-
LLL3
LLL3 is a structural analogue of STA-21 that acts as a novel STAT3 inhibitor.
-
SH5-07
SH5-07 (SH-5-07, SH 5-07) is a potent, selective small-molecule STAT3 inhibitor with IC50 of 3.9 uM.
-
N-Methylcytisine
N-Methylcytisine and N, N-dimethylcytisine did not displace 14C-tubocurarine at a concentration of .1 mM, cytisine was the only effective inhibitor of 14C-tubocurarine specific binding (Ki=7 nM).
