GSK-3008348 hydrochloride( GSK3008348 hydrochloride )

Catalog No. M12440 CAS No. 1629249-40-6

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

GSK-3008348 hydrochloride
Note

Research use only, not for human use.
Brief Description

GSK-3008348 hydrochloride is a novel potent, selective integrin αvβ6 antagonist for the treatment of idiopathic pulmonary fibrosis (IPF).
Description

GSK-3008348 hydrochloride is a novel potent, selective integrin αvβ6 antagonist for the treatment of idiopathic pulmonary fibrosis (IPF). Cystic Fibrosis Phase 1 Clinical.
In Vitro

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In Vivo

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Synonyms

GSK3008348 hydrochloride
Pathway

Cell Cycle/DNA Damage
Target

Integrin
Recptor

Integrin
Research Area

Other Indications
Indication

Fibrosis

CAS Number

1629249-40-6
Formula Weight

524.106
Molecular Formula

C29H38ClN5O2
Purity

>98% (HPLC)
Solubility

10 mM in DMSO
SMILES

O=C(O)C[C@@H](C1=CC=CC(N2N=C(C)C=C2C)=C1)CN3C[C@H](CCC4=NC5=C(CCCN5)C=C4)CC3.[H]Cl
Chemical Name

(S)-3-(3-(3,5-dimethyl-1H-pyrazol-1-yl)phenyl)-4-((R)-3-(2-(1,5,6,7-tetrahydro-1,8-naphthyridin-2-yl)ethyl)pyrrolidin-1-yl)butanoic acid hydrochloride