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Gly-Arg-Gly-Asp-Ser
CAS No. 96426-21-0
Gly-Arg-Gly-Asp-Ser( —— )
Catalog No. M30158 CAS No. 96426-21-0
Gly-Arg-Gly-Asp-Ser (GRGDS) GRGDS is a cell binding protein domain derived from the cell-binding region of fibronectin.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 43 | Get Quote |
|
| 5MG | 77 | Get Quote |
|
| 10MG | 122 | Get Quote |
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| 25MG | 194 | Get Quote |
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| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameGly-Arg-Gly-Asp-Ser
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NoteResearch use only, not for human use.
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Brief DescriptionGly-Arg-Gly-Asp-Ser (GRGDS) GRGDS is a cell binding protein domain derived from the cell-binding region of fibronectin.
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DescriptionGly-Arg-Gly-Asp-Ser (GRGDS) GRGDS is a cell binding protein domain derived from the cell-binding region of fibronectin.(In Vitro):Gly-Arg-Gly-Asp-Ser binds to integrin receptors αvβ3, with IC50 of 5 μM. Gly-Arg-Gly-Asp-Ser-immobilized TiO2 nanotubes enhance osteoblast-like cell (MG-63) adhesion, and significantly increased cell spreading and proliferation.
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In VitroGly-Arg-Gly-Asp-Ser binds to integrin receptors αvβ3, with IC50 of 5 μM. Gly-Arg-Gly-Asp-Ser-immobilized TiO2 nanotubes enhance osteoblast-like cell (MG-63) adhesion, and significantly increased cell spreading and proliferation.
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetIntegrin
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RecptorIC50: 5 μM (αvβ3), 6.5 μM (αvβ5)
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Research Area——
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Indication——
Chemical Information
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CAS Number96426-21-0
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Formula Weight490.47
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Molecular FormulaC17H30N8O9
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Purity>98% (HPLC)
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SolubilityDMSO : 100 mg/mL (203.89 mM; Need ultrasonic);H2O : 33.33 mg/mL (67.96 mM; Need ultrasonic)
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SMILES——
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Chemical NameSequence:Gly-Arg-Gly-Asp-Ser
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
Bernhagen D, et al. High-Affinity RGD-Knottin Peptide as a New Tool for Rapid Evaluation of the Binding Strength of Unlabeled RGD-Peptides to αvβ3, αvβ5, and α5β1 Integrin Receptors. Anal Chem. 2017 Jun 6;89(11):5991-5997.
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