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SNAP 5114

CAS No. 157604-55-2

SNAP 5114( SNAP5114 | SNAP-5114 | (S)-SNAP 5114 )

Catalog No. M12251 CAS No. 157604-55-2

A GABA transport inhibitor with IC50 of 5, 21, 388 and 140 uM for hGAT-3, rGAT-2, hGAT-1 and BGT-1, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 45 In Stock
5MG 42 In Stock
10MG 67 In Stock
25MG 155 In Stock
50MG 220 In Stock
100MG 319 In Stock
200MG 436 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    SNAP 5114
  • Note
    Research use only, not for human use.
  • Brief Description
    A GABA transport inhibitor with IC50 of 5, 21, 388 and 140 uM for hGAT-3, rGAT-2, hGAT-1 and BGT-1, respectively.
  • Description
    A GABA transport inhibitor with IC50 of 5, 21, 388 and 140 uM for hGAT-3, rGAT-2, hGAT-1 and BGT-1, respectively; increases thalamic GABA levels and is an anticonvulsant following systemic administration in vivo.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    SNAP5114 | SNAP-5114 | (S)-SNAP 5114
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    GAT
  • Recptor
    GAT
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    157604-55-2
  • Formula Weight
    505.61
  • Molecular Formula
    C30H35NO6
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (197.78 mM)
  • SMILES
    O=C([C@@H]1CN(CCOC(C2=CC=C(OC)C=C2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4)CCC1)O
  • Chemical Name
    1-[2-[tris(4-methoxyphenyl)methoxy]ethyl]-(S)-3-piperidinecarboxylic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Dhar TG, et al. J Med Chem. 1994 Jul 22;37(15):2334-42. 2. Christiansen B, et al. J Biol Chem. 2007 Jul 6;282(27):19331-41. 3. Doengi M, et al. Proc Natl Acad Sci U S A. 2009 Oct 13;106(41):17570-5. 4. Dvorzhak A, et al. J Physiol. 2010 Jul 1;588(Pt 13):2351-60.
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