Allopregnanolone

CAS No. 516-54-1

Allopregnanolone( 3α,5α-THP | SAGE547 | SAGE 547 | SAGE-547 )

Catalog No. M14799 CAS No. 516-54-1

An endogenous inhibitory pregnane neurosteroid and potent positive allosteric modulator of GABAA receptor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 49 In Stock
5MG 87 In Stock
10MG 142 In Stock
50MG 553 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Allopregnanolone
  • Note
    Research use only, not for human use.
  • Brief Description
    An endogenous inhibitory pregnane neurosteroid and potent positive allosteric modulator of GABAA receptor.
  • Description
    An endogenous inhibitory pregnane neurosteroid and potent positive allosteric modulator of GABAA receptor.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    3α,5α-THP | SAGE547 | SAGE 547 | SAGE-547
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    GAT
  • Recptor
    GABA
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    516-54-1
  • Formula Weight
    318.49346
  • Molecular Formula
    C21H34O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 10 mM
  • SMILES
    CC(=O)C1CCC2C1(CCC3C2CCC4C3(CCC(C4)O)C)C
  • Chemical Name
    Pregnan-20-one, 3-hydroxy-, (3α,5α)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Reddy DS, et al. Prog Brain Res. 2010;186:113-37. 2. Pinna G, et al. Neuropharmacology. 2000 Jan 28;39(3):440-8. 3. Kokate TG, et al. J Pharmacol Exp Ther. 1994 Sep;270(3):1223-9.
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