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Pipequaline
CAS No. 77472-98-1
Pipequaline( PK-8165 | PK8165 | PK 8165 )
Catalog No. M15927 CAS No. 77472-98-1
A clinically-effective anxiolytic that acts as a non-selective partial agonist of benzodiazepine receptor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 38 | In Stock |
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| 25MG | 113 | In Stock |
|
| 50MG | 211 | In Stock |
|
| 100MG | 365 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamePipequaline
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NoteResearch use only, not for human use.
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Brief DescriptionA clinically-effective anxiolytic that acts as a non-selective partial agonist of benzodiazepine receptor.
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DescriptionA clinically-effective anxiolytic that acts as a non-selective partial agonist of benzodiazepine receptor; exerts a partial suppression of activations by kainate, glutamate and acetylcholine in rats, also reduces the neuronal activation by kainate.
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In Vitro——
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In VivoIntravenously administered pipequaline exerts a partial suppression of activations by kainate, glutamate and acetylcholine. Microiontophoretic applications of pipequaline reduces the neuronal activation by kainate. Pipequaline produces dose-related decreases in motor activity. Pipequaline produces significant dose-related decreases in the number of head-dips made.
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SynonymsPK-8165 | PK8165 | PK 8165
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PathwayMembrane Transporter/Ion Channel
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TargetGAT
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RecptorGABAA
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Research Area——
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Indication——
Chemical Information
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CAS Number77472-98-1
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Formula Weight316.4394
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Molecular FormulaC22H24N2
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Purity>98% (HPLC)
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SolubilityDMSO: ≥ 32 mg/mL
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SMILESC1CNCCC1CCC2=CC(=NC3=CC=CC=C32)C4=CC=CC=C4
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Chemical NameQuinoline, 2-phenyl-4-[2-(4-piperidinyl)ethyl]-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. File SE. Br J Pharmacol. 1983 May;79(1):219-23.
2. Gee KW, et al. Brain Res. 1983 Mar 28;264(1):168-72.
3. Debonnel G, et al. Neuropharmacology. 1987 Sep;26(9):1337-42.
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