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Dexrazoxane hydrochloride
CAS No. 149003-01-0
Dexrazoxane hydrochloride( ICRF-187 hydrochloride )
Catalog No. M12061 CAS No. 149003-01-0
A derivative of EDTA that chelates iron and reduces the number of metal ions complexed with anthracycline and, consequently, decrease the formation of superoxide radicals.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 30 | In Stock |
|
| 5MG | 29 | In Stock |
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| 10MG | 44 | In Stock |
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| 25MG | 65 | In Stock |
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| 50MG | 86 | In Stock |
|
| 100MG | 113 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 295 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameDexrazoxane hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionA derivative of EDTA that chelates iron and reduces the number of metal ions complexed with anthracycline and, consequently, decrease the formation of superoxide radicals.
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DescriptionA derivative of EDTA that chelates iron and reduces the number of metal ions complexed with anthracycline and, consequently, decrease the formation of superoxide radicals; protects the heart against the cardiotoxic side effects of chemotherapeutic drugs.Chemotherapeutic Agents Approved.
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In Vitro——
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In Vivo——
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SynonymsICRF-187 hydrochloride
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research AreaCancer
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IndicationChemotherapeutic
Chemical Information
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CAS Number149003-01-0
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Formula Weight304.7301
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Molecular FormulaC11H17ClN4O4
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESO=C(CN(C[C@@H](N1CC(NC(C1)=O)=O)C)C2)NC2=O.[H]Cl
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Chemical Name1,3-Piperazinedione, 4,4'-[(1S)-1-methyl-1,2-ethanediyl]bis-, hydrochloride (1:?)
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Lipshultz SE, et al. N Engl J Med. 2004 Jul 8;351(2):145-53.
2. Bjelogrlic SK, et al. Exp Biol Med (Maywood). 2007 Dec;232(11):1414-24.
3. Jones RL, et al. Expert Rev Cardiovasc Ther. 2008 Nov;6(10):1311-7.
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