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URAT1 inhibitor 7
CAS No. 1632002-28-8
URAT1 inhibitor 7( —— )
Catalog No. M36929 CAS No. 1632002-28-8
URAT1 inhibitor 7 is a novel and potent inhibitor of the human uric acid transporter protein URAT1 (IC50:12 nM).URAT1 inhibitor 7 inhibits CYP2C9 with an IC50 of 4.2 μM.URAT1 inhibitor 7 can be used to study hyperuricemia and gout.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 459 | In Stock |
|
| 10MG | 657 | In Stock |
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| 25MG | 1026 | In Stock |
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| 50MG | 1386 | In Stock |
|
| 100MG | 1832 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 3655 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameURAT1 inhibitor 7
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NoteResearch use only, not for human use.
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Brief DescriptionURAT1 inhibitor 7 is a novel and potent inhibitor of the human uric acid transporter protein URAT1 (IC50:12 nM).URAT1 inhibitor 7 inhibits CYP2C9 with an IC50 of 4.2 μM.URAT1 inhibitor 7 can be used to study hyperuricemia and gout.
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DescriptionURAT1 inhibitor 7 (compound 10f) is a potent URAT1 inhibitor, with an IC50 of 12 nM. URAT1 inhibitor 7 exhibits microsomal stability (HLM <13 μL/min/mg). URAT1 inhibitor 7 also inhibits CYP2C9, with an IC50 of 4.2 μM. URAT1 inhibitor 7 can be used for gout research.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOAT
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Research Area——
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Indication——
Chemical Information
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CAS Number1632002-28-8
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Formula Weight428.82
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Molecular FormulaC19H10ClFN4O3S
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Purity>98% (HPLC)
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Solubility——
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SMILESN#CC1=CC=C(OC2=CC=C(C=C2C#N)S(=O)(=O)NC3=NC=C(F)C=C3)C=C1Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Storer R I, et al. The discovery and evaluation of diaryl ether heterocyclic sulfonamides as URAT1 inhibitors for the treatment of gout. MedChemComm, 2016:10.1039.C6MD00190D.
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