Biguanidinium-porphyrin
CAS No. 1014978-87-0
Biguanidinium-porphyrin( —— )
Catalog No. M35386 CAS No. 1014978-87-0
Biguanidinium-porphyrin is a phototoxic agent with anti-proliferative activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 296 | Get Quote |
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| 5MG | 425 | Get Quote |
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| 25MG | 984 | Get Quote |
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| 50MG | 1270 | Get Quote |
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| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameBiguanidinium-porphyrin
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NoteResearch use only, not for human use.
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Brief DescriptionBiguanidinium-porphyrin is a phototoxic agent with anti-proliferative activity.
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DescriptionBiguanidinium-porphyrin is a mitochondria-targeting photosensitizer. Biguanidinium-porphyrin distributes within cell membranes with a large component in vesicles that correlated to some extent with the lysosomes and, upon longer exposures, in mitochondria and the cytosolic membrane.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number1014978-87-0
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Formula Weight750.29
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Molecular FormulaC46H36ClN9
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Purity>98% (HPLC)
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Solubility——
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SMILESNC(NC(NC1=CC=C(/C2=C3C=CC(/C(C4=CC=CC=C4)=C5C=C/C(N/5)=C(C6=CC=CC=C6)/C(C=C/7)=NC7=C(C8=CC=CC=C8)/C9=CC=C2N9)=N\3)C=C1)=N)=N.Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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L-GLUCOSE
L-Glucose is an enantiomer of D-glucose. L-Glucose is not bioavailable to cells as an energy source because it cannot be phosphorylated by hexokinase.
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Dieugenol
Dieugenol is a neolignan that has been found in N. leucantha and has antioxidative and antiprotozoal activities. It inhibits the formation of thiobarbituric acid reactive substances (TBARS) and scavenges superoxide anions, but not hydroxyl radicals, in cell-free assays. It has anti-trypanosomal activity against T. cruzi amastigotes and trypomastigotes (IC50s=15.1 and 11.5 μM, respectively) but is cytotoxic to NCTC L-929 fibroblasts with a 50% cytotoxic concentration (CC50) value of 58.2 μM.2 Dieugenol (15 μM) disrupts the integrity of the T. cruzi trypomastigote plasma membrane but does not induce the production of reactive oxygen species (ROS) in trypomastigotes or LPS-stimulated and unstimulated isolated mouse peritoneal macrophages.
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