Cart
sales@molnova.com
PU-H54
CAS No. 1454619-13-6
PU-H54( PU H 54 )
Catalog No. M11959 CAS No. 1454619-13-6
A potent, selective Grp94 inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 69 | In Stock |
|
| 10MG | 112 | In Stock |
|
| 25MG | 259 | In Stock |
|
| 50MG | 375 | In Stock |
|
| 100MG | 533 | In Stock |
|
| 200MG | 724 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NamePU-H54
-
NoteResearch use only, not for human use.
-
Brief DescriptionA potent, selective Grp94 inhibitor.
-
DescriptionA potent, selective Grp94 inhibitor.
-
In Vitro——
-
In Vivo——
-
SynonymsPU H 54
-
PathwayCytoskeleton/Cell Adhesion Molecules
-
TargetHSP
-
RecptorHSP
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1454619-13-6
-
Formula Weight337.45
-
Molecular FormulaC18H19N5S
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (296.35 mM)
-
SMILESCC1=CC(C)=C(SC2=NC3=C(N)N=CN(CCCC#C)C3=N2)C=C1
-
Chemical Name8-((2,4-dimethylphenyl)thio)-3-(pent-4-yn-1-yl)-3H-purin-6-amine
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Khandelwal A, et al. ACS Med Chem Lett. 2017 Sep 1;8(10):1013-1018.
2. Crowley VM, et al. J Med Chem. 2016 Apr 14;59(7):3471-88.
molnova catalog
related products
-
Geldanamycin
Geldanamycin is a natural existing HSP90 inhibitor with Kd of 1.2 μM, specifically disrupts glucocorticoid receptor (GR)/HSP association.
-
HS-27
HS-27 is a fluorescently-tethered inhibitor of Hsp90 with SNX-5422 tethered via a PEG linker to a fluorescein isothiocyanate or FITC. HS-27 can be used in see-and-treat paradigms.
-
AT-533
AT-533 is a potent inhibitor of Hsp90 and HSV. AT-533 blocks the HIF-1α/VEGF/VEGFR-2 signaling pathway, leading to suppress tumor growth and angiogenesis.
