CTx0294885

CAS No. 1439934-41-4

CTx0294885( CTX0294885 | CTX 0294885 | CTX-0294885 )

Catalog No. M11865 CAS No. 1439934-41-4

CTX-0294885 is a a novel bisanilino pyrimidine; exhibits inhibitory activity against a broad range of kinases in vitro.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 84 In Stock
5MG 84 In Stock
10MG 123 In Stock
25MG 221 In Stock
50MG 369 In Stock
100MG 570 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    CTx0294885
  • Note
    Research use only, not for human use.
  • Brief Description
    CTX-0294885 is a a novel bisanilino pyrimidine; exhibits inhibitory activity against a broad range of kinases in vitro.
  • Description
    CTX-0294885 is a a novel bisanilino pyrimidine; exhibits inhibitory activity against a broad range of kinases in vitro, and further developed it into a Sepharose-supported kinase capture reagent.(In Vitro):CTX-0294885 is a kinase capture tool in large-scale kinome profiling experiments, with 185 kinases identified as total protein, and 179 identified from TiO2 enrichment for phosphopeptides in MDA-MB-231 cells (by quantitative MS).CTX-0294885 captures all members of the AKT family that is not identified from previous studies using other kinase capture reagents.
  • In Vitro
    CTX-0294885 is a kinase capture tool in large-scale kinome profiling experiments, with 185 kinases identified as total protein, and 179 identified from TiO2 enrichment for phosphopeptides in MDA-MB-231 cells (by quantitative MS).CTX-0294885 captures all members of the AKT family that is not identified from previous studies using other kinase capture reagents.
  • In Vivo
    ——
  • Synonyms
    CTX0294885 | CTX 0294885 | CTX-0294885
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Kinase capture reagent
  • Research Area
    Other Indications
  • Indication
    ——

Chemical Information

  • CAS Number
    1439934-41-4
  • Formula Weight
    437.93
  • Molecular Formula
    C22H24ClN7O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 10 mM
  • SMILES
    O=C(NC)C1=CC=CC=C1NC2=NC(NC3=CC=C(N4CCNCC4)C=C3)=NC=C2Cl
  • Chemical Name
    2-((5-chloro-2-((4-(piperazin-1-yl)phenyl)amino)pyrimidin-4-yl)amino)-N-methylbenzamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Zhang L, et al. J Proteome Res. 2013 Jul 5;12(7):3104-16.
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