XL-001
CAS No. 1426153-46-9
XL-001( XL001 )
Catalog No. M11799 CAS No. 1426153-46-9
XL-001 (XL001) is a novel specific CB2 inverse agonist with Ki of 0.5 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameXL-001
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NoteResearch use only, not for human use.
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Brief DescriptionXL-001 (XL001) is a novel specific CB2 inverse agonist with Ki of 0.5 nM.
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DescriptionXL-001 (XL001) is a novel specific CB2 inverse agonist with Ki of 0.5 nM; inhibits in a dose-dependent fashion the fibrogenic response induced by CB2 overexpression, CB2 agonist or transforming growth factor-β1, ameliorates kidney injury, fibrosis and inflammation in both the obstruction and ischemia/reperfusion models.
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In Vitro——
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In Vivo——
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SynonymsXL001
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PathwayGPCR/G Protein
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TargetCannabinoid Receptor
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RecptorCannabinoid Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number1426153-46-9
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Formula Weight438.586
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Molecular FormulaC25H30N2O3S
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Purity>98% (HPLC)
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Solubility——
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SMILESCCN(CC)C1=CC=C(C=C1)CN(C2=CC=C(C=C2)C)S(=O)(=O)C3=CC=C(C=C3)OC
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Chemical NameN-(4-(diethylamino)benzyl)-4-methoxy-N-(p-tolyl)benzenesulfonamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Zhou L, et al. Kidney Int. 2018 Aug 6. pii: S0085-2538(18)30397-1.
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