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CB1-IN-4
CAS No. 1429239-98-4
CB1-IN-4( DBPR211 | DBPR 211 | DBPR-211 | CB1-IN-1 )
Catalog No. M11811 CAS No. 1429239-98-4
CB1-IN-4 is a potent, selective, peripherally restricted cannabinoid-1 (CB1) receptor antagonist with Ki of 0.3 nM, EC50 of 3.0 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 226 | In Stock |
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| 2MG | 112 | In Stock |
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| 5MG | 189 | In Stock |
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| 10MG | 272 | In Stock |
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| 25MG | 446 | In Stock |
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| 50MG | 608 | In Stock |
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| 100MG | 820 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | 1646 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCB1-IN-4
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NoteResearch use only, not for human use.
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Brief DescriptionCB1-IN-4 is a potent, selective, peripherally restricted cannabinoid-1 (CB1) receptor antagonist with Ki of 0.3 nM, EC50 of 3.0 nM.
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DescriptionCB1-IN-4 is a potent, selective, peripherally restricted cannabinoid-1 (CB1) receptor antagonist with Ki of 0.3 nM, EC50 of 3.0 nM; possess a low probability to cross BBB as a peripherally restricted CB1R antagonist, exhibits significant weight-loss efficacy in DIO mice, also displays 163 clean off-target profiles and potential for treating obesity and the related metabolic syndrome.
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In Vitro——
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In Vivo——
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SynonymsDBPR211 | DBPR 211 | DBPR-211 | CB1-IN-1
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PathwayGPCR/G Protein
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TargetCannabinoid Receptor
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RecptorCannabinoid Receptor
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Research AreaNeurological Disease
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Indication——
Chemical Information
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CAS Number1429239-98-4
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Formula Weight751.6688
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Molecular FormulaC33H31Cl2F3N6O3S2
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESO=C(C1=NN(C2=CC=C(Cl)C=C2Cl)C(C3=CC=C(C#CC4=CC=C(C(F)(F)F)C=C4)S3)=C1CNS(=O)(N5CCCC5)=O)NN6CCCCC6
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Chemical Name1H-Pyrazole-3-carboxamide, 1-(2,4-dichlorophenyl)-N-1-piperidinyl-4-[[(1-pyrrolidinylsulfonyl)amino]methyl]-5-[5-[2-[4-(trifluoromethyl)phenyl]ethynyl]-2-thienyl]-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Chang CP, et al. J Med Chem. 2013 Dec 27;56(24):9920-33.
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