L-338192
CAS No. 1421702-02-4
L-338192( L338192 )
Catalog No. M11768 CAS No. 1421702-02-4
L-338192 is a small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 29 uM in AlphaScreen assay.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameL-338192
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NoteResearch use only, not for human use.
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Brief DescriptionL-338192 is a small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 29 uM in AlphaScreen assay.
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DescriptionL-338192 is a small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 29 uM in AlphaScreen assay; displays 4.8-fold and 3.8-fold selectivity over β-catenin/E-cadherin and β-catenin/APC interactions, respectively.
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In Vitro——
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In Vivo——
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SynonymsL338192
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PathwayWnt/Notch/Hedgehog
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TargetBeta-catenin
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RecptorBeta-catenin
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Research Area——
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Indication——
Chemical Information
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CAS Number1421702-02-4
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Formula Weight353.407
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Molecular FormulaC15H15NO5S2
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name(E)-3-(5-(2,3-dimethoxybenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)propanoic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Zhang M, et al. ACS Med Chem Lett. 2013 Jan 8;4(2):306-11.
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