BTK-IN-16( —— )

Catalog No. M35437 CAS No. 2883232-92-4

BTK-IN-16 is a potential inhibitor of wild-type BTK and C481S mutants.BTK-IN-16 can be used to study various autoimmune diseases and cancers caused by BTK.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

BTK-IN-16
Note

Research use only, not for human use.
Brief Description

BTK-IN-16 is a potential inhibitor of wild-type BTK and C481S mutants.BTK-IN-16 can be used to study various autoimmune diseases and cancers caused by BTK.
Description

BTK-IN-16 is a dual inhibitor of BTK wild type and C481S mutant of Bruton’s tyrosine kinase (BTK) with IC50s of 5.1 and 4.1 μM. BTK-IN-16 can be used for the research of autoimmune diseases and chronic lymphocytic leukemia.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Tyrosine Kinase
Target

BTK
Recptor

BTK
Research Area

——
Indication

——

Chemical Information

CAS Number

2883232-92-4
Formula Weight

282.3
Molecular Formula

C15H14N4O2
Purity

>98% (HPLC)
Solubility

——
SMILES

N=1C=CC=C(C1)NC=2N=CN=C3C=C(OC)C(OC)=CC32
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Kim T, et al. Two-Track Virtual Screening Approach to Identify the Dual Inhibitors of Wild Type and C481S Mutant of Bruton's Tyrosine Kinase. J Chem Inf Model. 2022 Aug 24.?

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