Cart
sales@molnova.com
WIN 55,212-2 mesylate
CAS No. 131543-23-2
WIN 55,212-2 mesylate( R)-(+)-WIN 55212 | WIN 55212-2 )
Catalog No. M11277 CAS No. 131543-23-2
WIN 55,212-2 mesylate (WIN 55212-2) is a potent cannabinoid receptor agonist with Ki of 62.3 and 3.3 nM for human recombinant CB1 and CB2 receptors, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 25MG | 184 | In Stock |
|
| 50MG | 260 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameWIN 55,212-2 mesylate
-
NoteResearch use only, not for human use.
-
Brief DescriptionWIN 55,212-2 mesylate (WIN 55212-2) is a potent cannabinoid receptor agonist with Ki of 62.3 and 3.3 nM for human recombinant CB1 and CB2 receptors, respectively.
-
DescriptionWIN 55,212-2 mesylate (WIN 55212-2) is a potent cannabinoid receptor agonist with Ki of 62.3 and 3.3 nM for human recombinant CB1 and CB2 receptors, respectively; increases extracellular glutamate levels, displaying a bell-shaped concentration-response curve at 0.01-100 nM; increases dialysate glutamate levels the prefrontal cortex from of the awake rats, also demonstrates anticonvulsant effect in vivo pre-treated with 20 mg/kg of pioglitazone.
-
In Vitro——
-
In Vivo——
-
SynonymsR)-(+)-WIN 55212 | WIN 55212-2
-
PathwayGPCR/G Protein
-
TargetCannabinoid Receptor
-
RecptorCB1R|CB2R
-
Research AreaNeurological Disease
-
Indication——
Chemical Information
-
CAS Number131543-23-2
-
Formula Weight522.616
-
Molecular FormulaC28H30N2O6S
-
Purity>98% (HPLC)
-
SolubilityDMSO: ≥ 34 mg/mL
-
SMILESO=C(C1=C(C)N2[C@H](CN3CCOCC3)COC4=CC=CC1=C24)C5=C6C=CC=CC6=CC=C5.CS(=O)(O)=O
-
Chemical NameMethanone, [(3R)-2,3-dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolo[1,2,3-de]-1,4-benzoxazin-6-yl]-1-naphthalenyl-, methanesulfonate (1:1)
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
-
Otenabant
A potent, and selective CB1 receptor antagonist with Ki of 0.7 nM/0.12 nM in binding and functional assays respectively; has low affinity (Ki=7600 nM) for human CB2 receptors; reverses cannabinoid agonist mediated responses, reduces food intake, and increases energy expenditure and fat oxidation in rodents.ObesityPhase 3 Discontinued
-
CB2R/FAAH modulator-...
CB2R/FAAH modulator-3 (compound 27) is a modulator targeting CB2R and FAAH, acting as a CB2R agonist with a Ki value of 20.1 nM and a CB1R agonist with a Ki value of 67.6 nM, while inhibiting FAAH with an IC50 value of 3.4 μM.
-
Drinabant
Drinabant is an orally active CB1 receptor antagonist. Drinabant inhibits the agonist-stimulated calcium signal with IC50 values of 25 nM and 10 nM for the hCB1-R and rCB1-R, respectively, and is ineffective for the hCB2-R.
