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SMM-295
CAS No. 1054451-22-7
SMM-295( SMM295 | SMM 295 )
Catalog No. M10252 CAS No. 1054451-22-7
A novel potent, selective cannabinoid receptor 2 (CB2) agonist with Ki of 12 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameSMM-295
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NoteResearch use only, not for human use.
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Brief DescriptionA novel potent, selective cannabinoid receptor 2 (CB2) agonist with Ki of 12 nM.
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DescriptionA novel potent, selective cannabinoid receptor 2 (CB2) agonist with Ki of 12 nM, >30-fold selectivity over CB1; reduces cAMP production with a 66-fold selectivity for the CB2 versus the cannabinoid receptor 1 (CB1) in HEK-293 cells; reduces tubular damage and plasma markers of renal dysfunction (i.e., creatinine and NGAL) in acute kidney injury mice.
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In Vitro——
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In Vivo——
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SynonymsSMM295 | SMM 295
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PathwayGPCR/G Protein
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TargetCannabinoid Receptor
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RecptorCannabinoid Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number1054451-22-7
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Formula Weight324.438
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Molecular FormulaC20H20O2S
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name3'-methyl-4-(2-(thiophen-2-yl)propan-2-yl)-[1,1'-biphenyl]-2,6-diol
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Pressly JD, et al. J Pharmacol Exp Ther. 2017 Nov 29. pii: jpet.117.245522.
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