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PF-05212377
CAS No. 1226793-34-5
PF-05212377( SAM-760 | PF 5212377 )
Catalog No. M10869 CAS No. 1226793-34-5
PF-05212377 (SAM-760, PF 5212377) is a potent and selective 5-HT6 receptor antagonist with potential therapy for the symptomatic treatment of mild to moderate Alzheimer's disease.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NamePF-05212377
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NoteResearch use only, not for human use.
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Brief DescriptionPF-05212377 (SAM-760, PF 5212377) is a potent and selective 5-HT6 receptor antagonist with potential therapy for the symptomatic treatment of mild to moderate Alzheimer's disease.
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DescriptionPF-05212377 (SAM-760, PF 5212377) is a potent and selective 5-HT6 receptor antagonist with potential therapy for the symptomatic treatment of mild to moderate Alzheimer's disease.Alzheimer Disease Phase 2 Clinical
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In Vitro——
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In Vivo——
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SynonymsSAM-760 | PF 5212377
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PathwayGPCR/G Protein
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Target5-HT Receptor
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Recptor5-HT Receptor
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Research AreaNeurological Disease
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IndicationAlzheimer Disease
Chemical Information
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CAS Number1226793-34-5
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Formula Weight356.444
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Molecular FormulaC18H20N4O2S
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name2-methyl-1-(phenylsulfonyl)-4-(piperazin-1-yl)-1H-benzo[d]imidazole
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Fullerton T, et al. Alzheimers Res Ther. 2018 Apr 5;10(1):38.
2. Fullerton T, et al. Alzheimers Res Ther. 2018 Apr 5;10(1):38.
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