Pandacostat

CAS No. 1224158-00-2

Pandacostat( —— )

Catalog No. M10858 CAS No. 1224158-00-2

Pandacostat is the first nonselective HDAC inhibitor (pan-HDACi).

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    Pandacostat
  • Note
    Research use only, not for human use.
  • Brief Description
    Pandacostat is the first nonselective HDAC inhibitor (pan-HDACi).
  • Description
    Pandacostat is the first nonselective HDAC inhibitor (pan-HDACi) with Ki of 0.12/0.07/0.95/0.18/0.032/1.1/0.5/1.4 uM for HDAC1/2/3/4/5/6/7/8/9, respectively; exhibts activity in biochemical and cellular assay systems.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    HDAC
  • Recptor
    HDAC
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1224158-00-2
  • Formula Weight
    357.322
  • Molecular Formula
    C17H15N3O6
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    (E)-3-[4-[[[(E)-(2,3-dihydroxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]amino]carbamoyl]phenyl]-N-hydroxyprop-2-enamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Bradner JE, et al. Nat Chem Biol. 2010 Mar;6(3):238-243.
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