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PF-04929113 Mesylate
CAS No. 1173111-67-5
PF-04929113 Mesylate( SNX-5422 Mesylate | PF04929113 Mesylate | SNX5422 Mesylate )
Catalog No. M10581 CAS No. 1173111-67-5
The prodrug of PF-04928473 (SNX-2112), a potent, orally bioavailable HSP90 inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 233 | In Stock |
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| 2MG | 97 | In Stock |
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| 5MG | 154 | In Stock |
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| 10MG | 288 | In Stock |
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| 25MG | 418 | In Stock |
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| 50MG | 603 | In Stock |
|
| 100MG | 860 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 1739 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamePF-04929113 Mesylate
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NoteResearch use only, not for human use.
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Brief DescriptionThe prodrug of PF-04928473 (SNX-2112), a potent, orally bioavailable HSP90 inhibitor.
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DescriptionThe prodrug of PF-04928473 (SNX-2112), a potent, orally bioavailable HSP90 inhibitor; inhibits several signaling pathways and induces apoptosis in CRPC LNCaP tumors in vivo.Blood Cancer Phase 1 Clinical.
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In Vitro——
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In Vivo——
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SynonymsSNX-5422 Mesylate | PF04929113 Mesylate | SNX5422 Mesylate
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PathwayCytoskeleton/Cell Adhesion Molecules
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TargetHSP
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RecptorHSP90|HER2
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Research AreaCancer
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IndicationBlood cancer
Chemical Information
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CAS Number1173111-67-5
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Formula Weight617.6377
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Molecular FormulaC26H34F3N5O7S
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESCC1(CC2=C(C(=O)C1)C(=NN2C3=CC(=C(C=C3)C(=O)N)NC4CCC(CC4)OC(=O)CN)C(F)(F)F)C.CS(=O)(=O)O
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Chemical NameGlycine, trans-4-[[2-(aminocarbonyl)-5-[4,5,6,7-tetrahydro-6,6-dimethyl-4-oxo-3-(trifluoromethyl)-1H-indazol-1-yl]phenyl]amino]cyclohexyl ester, methanesulfonate (1:1)
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Lamoureux F, et al. Clin Cancer Res. 2011 Jul 15;17(14):4916.
2. Rajan A, et al. Clin Cancer Res. 2011 Nov 1;17(21):6831-9.
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