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BIX02188 (c)

CAS No. 1094614-84-2

BIX02188 (c)( —— )

Catalog No. M10367 CAS No. 1094614-84-2

BIX02188 is a selective inhibitor of MEK5 with IC50 of 4.3 nM, also inhibits ERK5 catalytic activity with IC50 of 810 nM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	139	In Stock
2MG	57	In Stock
5MG	122	In Stock
10MG	229	In Stock
25MG	345	In Stock
50MG	507	In Stock
100MG	730	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

BIX02188 (c)
Note

Research use only, not for human use.
Brief Description

BIX02188 is a selective inhibitor of MEK5 with IC50 of 4.3 nM, also inhibits ERK5 catalytic activity with IC50 of 810 nM.
Description

BIX02188 is a selective inhibitor of MEK5 with IC50 of 4.3 nM, also inhibits ERK5 catalytic activity with IC50 of 810 nM, and does not inhibit closely related kinases MEK1, MEK2, ERK2, and JNK2.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

MAPK/ERK Signaling
Target

ERK
Recptor

ERK5| MEK1| MEK2| MEK5| TGFβR1
Research Area

Cancer
Indication

——

Chemical Information

CAS Number

1094614-84-2
Formula Weight

412.48
Molecular Formula

C25H24N4O2
Purity

>98% (HPLC)
Solubility

DMSO: 100 mM
SMILES

CN(C)CC1=CC(=CC=C1)N/C(=C\2/C3=C(C=C(C=C3)C(=O)N)NC2=O)/C4=CC=CC=C4
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Tatake RJ, et al. Biochem Biophys Res Commun, 2008, 377(1), 120-125.

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