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ISRIB (trans-isomer)
CAS No. 1597403-47-8
ISRIB (trans-isomer)( trans-ISRIB )
Catalog No. M12282 CAS No. 1597403-47-8
ISRIB (trans-isomer), the trans-isomer of ISRIB, is a potent and selective PERK inhibitor with IC50 of 5 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 39 | In Stock |
|
| 5MG | 63 | In Stock |
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| 10MG | 95 | In Stock |
|
| 25MG | 186 | In Stock |
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| 50MG | 319 | In Stock |
|
| 100MG | 575 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 1237 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameISRIB (trans-isomer)
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NoteResearch use only, not for human use.
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Brief DescriptionISRIB (trans-isomer), the trans-isomer of ISRIB, is a potent and selective PERK inhibitor with IC50 of 5 nM.
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DescriptionISRIB (trans-isomer), the trans-isomer of ISRIB, is a potent and selective PERK inhibitor with IC50 of 5 nM.
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In Vitro——
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In Vivo——
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Synonymstrans-ISRIB
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PathwayMAPK/ERK Signaling
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TargetERK
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RecptorPERK
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Research AreaNeurological Disease
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Indication——
Chemical Information
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CAS Number1597403-47-8
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Formula Weight451.34
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Molecular FormulaC22H24Cl2N2O4
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Purity>98% (HPLC)
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SolubilityDMSO:4 mg/mL (8.86 mM); Ethanol:<1 mg/mL (<1 mM); Water：<1 mg/mL (<1 mM)
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SMILESO=C(N[C@H]1CC[C@H](NC(COC2=CC=C(Cl)C=C2)=O)CC1)COC3=CC=C(Cl)C=C3
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Chemical NameN,N'-((1r,4r)-cyclohexane-1,4-diyl)bis(2-(4-chlorophenoxy)acetamide)
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Sidrauski C, et al. Elife. 2013, 2, e00498.
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