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AZ32（b）
CAS No.
AZ32（b） ( —— )
Catalog No. M19313 CAS No.
AZ32 is an orally bioavailable and blood-brain barrier-penetratingATMinhibitor with anIC50of <6.2 nM for ATM enzyme, and anIC50of 0.31 μM for ATM in cell.
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 107 | Get Quote |
|
| 10MG | 191 | Get Quote |
|
| 25MG | 467 | Get Quote |
|
| 50MG | 719 | Get Quote |
|
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameAZ32（b）
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NoteResearch use only, not for human use.
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Brief DescriptionAZ32 is an orally bioavailable and blood-brain barrier-penetratingATMinhibitor with anIC50of <6.2 nM for ATM enzyme, and anIC50of 0.31 μM for ATM in cell.
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DescriptionAZ32 is an orally bioavailable and blood-brain barrier-penetratingATMinhibitor with anIC50of <6.2 nM for ATM enzyme, and anIC50of 0.31 μM for ATM in cell.
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Synonyms——
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PathwayMAPK/ERK Signaling
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TargetERK
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RecptorATM;ATM (in cell)
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Research Area——
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Indication——
Chemical Information
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CAS Number--
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Formula Weight328.37
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Molecular FormulaC20H16N4O
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Purity98%
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Solubility——
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SMILESCNC(=O)c1ccc(cc1)c2cnc3cnc(cn23)c4ccccc4
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Karlin J, et al. Orally Bioavailable and Blood-Brain Barrier-Penetrating ATM Inhibitor (AZ32) Radiosensitizes Intracranial Gliomas in Mice. Mol Cancer Ther. 2018 Aug;17(8):1637-1647.
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