HAP-12
CAS No. 1078164-85-8
HAP-12( HAP12 )
Catalog No. M10314 CAS No. 1078164-85-8
HAP-12 is a small molecule HBV capsid assembly effector that inhibits HBV DNA replication with EC50 of 0.5 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameHAP-12
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NoteResearch use only, not for human use.
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Brief DescriptionHAP-12 is a small molecule HBV capsid assembly effector that inhibits HBV DNA replication with EC50 of 0.5 uM.
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DescriptionHAP-12 is a small molecule HBV capsid assembly effector that inhibits HBV DNA replication with EC50 of 0.5 uM.
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In Vitro——
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In Vivo——
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SynonymsHAP12
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PathwayMicrobiology/Virology
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TargetHBV
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RecptorHBV
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Research Area——
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Indication——
Chemical Information
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CAS Number1078164-85-8
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Formula Weight444.891
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Molecular FormulaC22H22ClFN4O3
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Namemethyl 4-(2-chloro-4-fluorophenyl)-6-(morpholinomethyl)-2-(pyridin-2-yl)-1,4-dihydropyrimidine-5-carboxylate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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GLP-26
GLP-26 is a novel potent HBV capsid modulator that reduces secreted HBeAg in HepNTCPDL cells transfected with HBV wild type with EC50 of 0.7 uM.
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ccc_R08
ccc_R08 is an orally available HBV cccDNA inhibitor that reduces extracellular levels of HBV DNA, HBsAg, and HBeAg in a dose-dependent manner. ccc_R08 is investigational for use in the treatment of HBV infections. ccc_R08 has been shown to be effective in the treatment of hepatitis C virus (HCV).
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Alisol F
Alisol F is a natural product from Alisma plantago-aquatica Linn and has many activities.Alisol F shows anti-inflammatory activities and liver protection through the inhibition of MAPK, STAT3, and NF-κB activation in vitro and in vivo, it suppresses iNOS induction.
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