Irinotecan Hydrochloride
CAS No. 100286-90-6
Irinotecan Hydrochloride( —— )
Catalog No. M10029 CAS No. 100286-90-6
Irinotecan Hcl(CPT-11 Hcl) prevents DNA from unwinding by inhibition of topoisomerase 1.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 57 | In Stock |
|
| 100MG | 86 | In Stock |
|
| 200MG | 124 | In Stock |
|
| 500MG | 254 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameIrinotecan Hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionIrinotecan Hcl(CPT-11 Hcl) prevents DNA from unwinding by inhibition of topoisomerase 1.
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DescriptionIrinotecan Hcl(CPT-11 Hcl) prevents DNA from unwinding by inhibition of topoisomerase 1.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetTopoisomerase
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RecptorTopo I
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number100286-90-6
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Formula Weight623.14
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Molecular FormulaC33H39ClN4O6
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Purity>98% (HPLC)
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SolubilitySoluble in Water
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SMILESCCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)[C@@]5(CC)O)OC(=O)N6CCC(CC6)N7CCCCC7.Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Exatecan Mesylate
Exatecan Mesylate is a DNA topoisomerase I inhibitor (IC50: 2.2 μM, 0.975 μg/mL).Exatecan Mesylate (DX-8951f) significantly inhibits the proliferation of several cancer cell lines, with mean GI50s of 2.02 ng/mL, 2.92 ng/mL, 1.53 ng/mL, and 0.877 ng/mL for breast cancer cells, colon cancer cells, stomach cancer cells and lung cancer cells, respectively.
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Idarubicin
Idarubicin (4-Demethoxydaunorubicin;IMI-30;NSC 256439) is an anthracycline antileukemic that inserts into DNA and prevents DNA unwinding by interfering with the enzyme Topoisomerase II in cancer cells.
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Idarubicin hydrochlo...
An anthracycline antileukemic that inserts into DNA and prevents DNA unwinding by interfering with the enzyme Topoisomerase II in cancer cells.
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