Irinotecan Hydrochloride

CAS No. 100286-90-6

Irinotecan Hydrochloride( —— )

Catalog No. M10029 CAS No. 100286-90-6

Irinotecan Hcl(CPT-11 Hcl) prevents DNA from unwinding by inhibition of topoisomerase 1.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 65 In Stock
10MG 29 In Stock
25MG 42 In Stock
50MG 59 In Stock
100MG 89 In Stock
200MG 128 In Stock
500MG 262 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Irinotecan Hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Irinotecan Hcl(CPT-11 Hcl) prevents DNA from unwinding by inhibition of topoisomerase 1.
  • Description
    Irinotecan Hcl(CPT-11 Hcl) prevents DNA from unwinding by inhibition of topoisomerase 1.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    Topoisomerase
  • Recptor
    Topo I
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    100286-90-6
  • Formula Weight
    623.14
  • Molecular Formula
    C33H39ClN4O6
  • Purity
    >98% (HPLC)
  • Solubility
    Soluble in Water
  • SMILES
    CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)[C@@]5(CC)O)OC(=O)N6CCC(CC6)N7CCCCC7.Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Yoshikawa M, et al. Int J Y. 2004 Jul 20;110(6):921-7.
molnova catalog
related products
  • Topoisomerase II inh...

    Topoisomerase II inhibitor 14 is a potent topoisomerase II inhibitor with anticancer and antioxidant activities.Topoisomerase II inhibitor 14 induces apoptosis and blocks the cell cycle in S phase.

  • Etoposide

    Etoposide is a semisynthetic derivative of podophyllotoxin, which inhibits DNA synthesis via topoisomerase II inhibition activity.

  • Topovale

    Topovale is a potent inhibitor of topoisomerase I. Topovale inhibits hypoxia-mediated accumulation of hypoxia-inducible factor-1alpha.