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Lusutrombopag

CAS No. 1110766-97-6

Lusutrombopag( S-888711 )

Catalog No. M10412 CAS No. 1110766-97-6

An orally bioavailable, small molecule thrombopoietin (TPO) receptor agonist.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 151 In Stock
10MG 241 In Stock
25MG 466 In Stock
50MG 677 In Stock
100MG 954 In Stock
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Biological Information

  • Product Name
    Lusutrombopag
  • Note
    Research use only, not for human use.
  • Brief Description
    An orally bioavailable, small molecule thrombopoietin (TPO) receptor agonist.
  • Description
    An orally bioavailable, small molecule thrombopoietin (TPO) receptor agonist; acts selectively on the human thrombopoietin receptor and activates signal transduction pathways that promote the proliferation and differentiation of bone marrow cells into megakaryocytes, thereby increasing platelet levels; Other Indication Approved.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    S-888711
  • Pathway
    Immunology/Inflammation
  • Target
    CD110
  • Recptor
    CD110
  • Research Area
    Other Indications
  • Indication
    Other Disease

Chemical Information

  • CAS Number
    1110766-97-6
  • Formula Weight
    591.5458
  • Molecular Formula
    C29H32Cl2N2O5S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 33 mg/mL
  • SMILES
    O=C(O)/C(C)=C/C1=C(Cl)C=C(C(NC2=NC(C3=CC=CC([C@@H](OCCCCCC)C)=C3OC)=CS2)=O)C=C1Cl
  • Chemical Name
    2-Propenoic acid, 3-[2,6-dichloro-4-[[[4-[3-[(1S)-1-(hexyloxy)ethyl]-2-methoxyphenyl]-2-thiazolyl]amino]carbonyl]phenyl]-2-methyl-, (2E)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kim ES. Drugs. 2016 Jan;76(1):155-8. 2. Sakamaki A, et al. Clin J Gastroenterol. 2017 Jun;10(3):261-264.
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