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LY2183240
CAS No. 874902-19-9
LY2183240( —— )
Catalog No. M24889 CAS No. 874902-19-9
LY2183240 inhibits fatty acid amide hydrolase (FAAH) activity (IC50 = 12.4 nM). LY2183240 is a novel and highly effective blocker of anandamide uptake (IC50 = 270 pM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 35 | In Stock |
|
| 10MG | 58 | In Stock |
|
| 25MG | 120 | In Stock |
|
| 50MG | 228 | In Stock |
|
| 100MG | 356 | In Stock |
|
| 500MG | 836 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameLY2183240
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NoteResearch use only, not for human use.
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Brief DescriptionLY2183240 inhibits fatty acid amide hydrolase (FAAH) activity (IC50 = 12.4 nM). LY2183240 is a novel and highly effective blocker of anandamide uptake (IC50 = 270 pM).
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DescriptionLY2183240 inhibits fatty acid amide hydrolase (FAAH) activity (IC50 = 12.4 nM). LY2183240 is a novel and highly effective blocker of anandamide uptake (IC50 = 270 pM).
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In Vitro——
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In VivoLY2183240 (3-30mg/kg; i.p.) dose-dependently attenuates formalin-induced paw-licking pain behavior in the formalin model of persistent pain mechanisms. Animal Model:Male Sprague-Dawley rats (Formalin Pain Model)Dosage:3, 10, 30 mg/kg Administration:I.p.Result:Dose-dependently attenuated formalin-induced paw-licking pain behavior in the formalin model of persistent pain mechanisms.
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Synonyms——
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PathwayAutophagy
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TargetAutophagy
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RecptorAutophagy|FAAH
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Research Area——
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Indication——
Chemical Information
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CAS Number874902-19-9
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Formula Weight307.35
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Molecular FormulaC17H17N5O
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Purity>98% (HPLC)
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SolubilityDMSO:50 mg/mL (162.68 mM; Need ultrasonic)
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SMILESO=C(N(C)C)N1N=NN=C1CC(C=C2)=CC=C2C3=CC=CC=C3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Dickason-Chesterfield AK, et al. Pharmacological characterization of endocannabinoid transport and fatty acid amide hydrolase inhibitors. Cell Mol Neurobiol. 2006 Jul-Aug;26(4-6):407-23.
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