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L-KAWAIN
CAS No. 500-64-1
L-KAWAIN( —— )
Catalog No. M18662 CAS No. 500-64-1
Kawain is one of the six major kavalactones found in the Piper methysticum (kava) plant; reversible inhibitor of MAO-B.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 35 | In Stock |
|
| 10MG | 50 | In Stock |
|
| 25MG | 82 | In Stock |
|
| 50MG | 120 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameL-KAWAIN
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NoteResearch use only, not for human use.
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Brief DescriptionKawain is one of the six major kavalactones found in the Piper methysticum (kava) plant; reversible inhibitor of MAO-B.
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DescriptionKawain is one of the six major kavalactones found in the Piper methysticum (kava) plant; reversible inhibitor of MAO-B.(In Vitro):(+)-Kavain (10-300 μM) enhances GABA-elicited responses in a concentration-dependent manner. The modulatory effect of Kavain is moderate, with only 170±23% of enhancement measured at 300 μM. (+)-Kavain inhibits TNF-α secretion in cells via suppression of LITAF.
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In Vitro(+)-Kavain (10-300 μM) enhances GABA-elicited responses in a concentration-dependent manner. The modulatory effect of Kavain is moderate, with only 170±23% of enhancement measured at 300 μM. (+)-Kavain inhibits TNF-α secretion in cells via suppression of LITAF.
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In Vivo——
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetBACE
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RecptorMonoamine transporter
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Research Area——
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Indication——
Chemical Information
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CAS Number500-64-1
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Formula Weight230.26
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Molecular FormulaC14H14O3
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 125 mg/mL; 542.86 mM
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SMILESCOC1=CC(=O)O[C@H](C1)\C=C\c1ccccc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Uebelhack R, et al. Inhibition of platelet MAO-B by kava pyrone-enriched extract from Piper methysticum Forster (kava-kava). Pharmacopsychiatry. 1998 Sep;31(5):187-92.
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