LY3202626( LY 3202626 | LY-3202626 )

Catalog No. M12433 CAS No. 1628690-73-2

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

LY3202626
Note

Research use only, not for human use.
Brief Description

LY3202626 is a small molecule non-selective BACE1 inhibitor, causes dose-dependent reductions in CSF and plasma Aβ concentrations.
Description

LY3202626 is a small molecule non-selective BACE1 inhibitor, causes dose-dependent reductions in CSF and plasma Aβ concentrations, shows potential for the treatment of Alzheimer's disease.Alzheimer Disease Phase 2 Clinical.
In Vitro

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In Vivo

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Synonyms

LY 3202626 | LY-3202626
Pathway

Metabolic Enzyme/Protease
Target

BACE
Recptor

BACE
Research Area

Neurological Disease
Indication

Alzheimer Disease

CAS Number

1628690-73-2
Formula Weight

498.513
Molecular Formula

C22H20F2N8O2S
Purity

>98% (HPLC)
Solubility

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SMILES

O=C(C1=NC=C(OC)N=C1)NC2=CC=C(F)C([C@@]34N=C(N)SC[C@]3([H])CN(C5=NC=C(F)C=N5)C4)=C2
Chemical Name

N-(3-((4aR,7aS)-2-amino-6-(5-fluoropyrimidin-2-yl)-4a,5,6,7-tetrahydropyrrolo[3,4-d][1,3]thiazin-7a(4H)-yl)-4-fluorophenyl)-5-methoxypyrazine-2-carboxamide