Kinetensin

CAS No. 103131-69-7

Kinetensin ( Kinetensin (human) )

Catalog No. M29815 CAS No. 103131-69-7

Kinetensin is a neurotensin-like peptide.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 214 Get Quote
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Biological Information

  • Product Name
    Kinetensin
  • Note
    Research use only, not for human use.
  • Brief Description
    Kinetensin is a neurotensin-like peptide.
  • Description
    Kinetensin is a neurotensin-like peptide.(In Vitro):The peptide kinetensin isolated from pepsin-treated human plasma induces a dose-dependent release of histamine when exposed to rat peritoneal mast cells. The threshold concentration is around 1 μM, the ED50 is 10 μM, and the optimal concentration of between 100 to 1000 μM released 80% of the total histamine. Kinetensin is 10 to 100 times less potent than neurotensin and equipotent with the opioid peptide dynorphin. The histamine release is clearly temperature-dependent, with no release occurring at 0 or 45 °C and with an optimum around 37 °C. The histamine release is significantly reduced in the absence of extracellular calcium.(In Vivo):Kinetensin also induces a dose-dependent increase in vascular permeability when injected intradermally into rats.
  • Synonyms
    Kinetensin (human)
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Neurotensin Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    103131-69-7
  • Formula Weight
    1172.4
  • Molecular Formula
    C56H85N17O11
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

Mogard MH, et al. The amino acid sequence of kinetensin, a novel peptide isolated from pepsin-treated human plasma: homology with human serum albumin, neurotensin and angiotensin. Biochem Biophys Res Commun. 1986 May 14;136(3):983-8.
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