Cart
sales@molnova.com
Acid Ceramidase-IN-1
CAS No. 2415225-30-6
Acid Ceramidase-IN-1( —— )
Catalog No. M35177 CAS No. 2415225-30-6
Acid Ceramidase-IN-1 is a highly effective, orally bioavailable inhibitor of acid ceramidase (AC, ASAH-1) with an IC50 of 0.166 μM and exhibits exceptional brain penetration capabilities in mice.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 163 | In Stock |
|
| 5MG | 250 | In Stock |
|
| 10MG | 398 | In Stock |
|
| 25MG | 799 | In Stock |
|
| 50MG | 1279 | In Stock |
|
| 100MG | 1917 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameAcid Ceramidase-IN-1
-
NoteResearch use only, not for human use.
-
Brief DescriptionAcid Ceramidase-IN-1 is a highly effective, orally bioavailable inhibitor of acid ceramidase (AC, ASAH-1) with an IC50 of 0.166 μM and exhibits exceptional brain penetration capabilities in mice.
-
DescriptionAcid Ceramidase-IN-1 is a potent and oral bioavailable acid ceramidase (AC, ASAH-1) inhibitor (hAC IC50=0.166 μM). Acid Ceramidase-IN-1 has excellent brain penetration in mice.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorOthers
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2415225-30-6
-
Formula Weight331.41
-
Molecular FormulaC18H25N3O3
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 50 mg/mL (150.87 mM; Ultrasonic (<60°C)
-
SMILESCC(C)CNC(=O)n1c2ccc(cc2oc1=O)C1CCN(C)CC1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Di Martino S, et al. Lead Optimization of Benzoxazolone Carboxamides as Orally Bioavailable and CNS Penetrant Acid Ceramidase Inhibitors. J Med Chem. 2020;63(7):3634-3664. ?
molnova catalog
related products
-
Buserelin Acetate
Buserelin Acetate is an agonist of gonadotropin-releasing hormone receptor(GnRHR).
-
EGCG Octaacetate
EGCG Octaacetate a prodrug of EGCG is utilized to enhance the stability and bioavailability of EGCG in vivo. It has high efficacy bioavailability anti-oxidation and anti-angiogenesis capacities.
-
D-(+)-Fucose
D-(+)-Fucose is a hexose deoxy sugar found on N-linked glycans that appears on the cell surface of mammalian and plant cells.
