JNJ-632

CAS No. 1572510-42-9

JNJ-632 ( JNJ632 )

Catalog No. M12246 CAS No. 1572510-42-9

JNJ-632 (JNJ632) is a novel potent HVV capsid assembly modulator and HBV replication inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 43 In Stock
5MG 71 In Stock
10MG 114 In Stock
25MG 230 In Stock
50MG 354 In Stock
100MG 527 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    JNJ-632
  • Note
    Research use only, not for human use.
  • Brief Description
    JNJ-632 (JNJ632) is a novel potent HVV capsid assembly modulator and HBV replication inhibitor.
  • Description
    JNJ-632 (JNJ632) is a novel potent HVV capsid assembly modulator and HBV replication inhibitor with EC50 of 100-200 nM for genotypes A-D; does not show cytotoxicity for HepG2 cells (CC50>100 uM); dose-dependently reduces intracellular HBV RNA levels as well as HBe/cAg and HBsAg levels in the cell culture supernatant.
  • Synonyms
    JNJ632
  • Pathway
    Microbiology/Virology
  • Target
    HBV
  • Recptor
    HBV
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1572510-42-9
  • Formula Weight
    378.42
  • Molecular Formula
    C18H19FN2O4S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 125 mg/mL330.32 mM
  • SMILES
    O=C(NC1=CC=C(F)C(C)=C1)C2=CC=CC(S(=O)(N[C@@H]3COCC3)=O)=C2
  • Chemical Name
    (S)-N-(4-fluoro-3-methylphenyl)-3-(N-(tetrahydrofuran-3-yl)sulfamoyl)benzamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Berke JM, et al. Antimicrob Agents Chemother. 2017 Jul 25;61(8). pii: e00560-17.
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