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Home - Products - GPCR/G Protein - Dopamine Receptor - JNJ-37822681

JNJ-37822681

CAS No. 935776-74-2

JNJ-37822681( JNJ 37822681 | JNJ37822681 )

Catalog No. M27891 CAS No. 935776-74-2

JNJ-37822681 is a novel, highly selective dopamine D? receptor antagonist characterized by a rapid dissociation rate from the dopamine D? receptor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    JNJ-37822681
  • Note
    Research use only, not for human use.
  • Brief Description
    JNJ-37822681 is a novel, highly selective dopamine D? receptor antagonist characterized by a rapid dissociation rate from the dopamine D? receptor.
  • Description
    JNJ-37822681 is a novel, highly selective dopamine D? receptor antagonist characterized by a rapid dissociation rate from the dopamine D? receptor.(In Vivo):JNJ-37822681 occupied D2 receptors in rat brain at relatively low doses (ED50 = 0.39 mg/kg) and was effective in animal models of psychosis (e.g., inhibition of apomorphine-induced stereotypy or D-amphetamine/phencyclidine-induced hyperlocomotion).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    JNJ 37822681 | JNJ37822681
  • Pathway
    GPCR/G Protein
  • Target
    Dopamine Receptor
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    935776-74-2
  • Formula Weight
    372.343
  • Molecular Formula
    C17H17F5N4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Fc1ccc(CN2CCC(CC2)Nc2ccc(nn2)C(F)(F)F)cc1F
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Zhihui Xiao, et al. A new flavanone glucoside from Abrus precatorius.Chemistry of Natural Compounds volume 48, pages 565-567 (2012).
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