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JB062
CAS No. 2417988-00-0
JB062( —— )
Catalog No. M36106 CAS No. 2417988-00-0
JB062 is a chemical compound acting as a nonmuscle myosin inhibitor, exhibiting IC50 values of 1.6, 5.4, and >100 μM against skeletal muscle myosin, cardiac muscle myosin, and smooth muscle myosin II, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 296 | Get Quote |
|
| 5MG | 466 | Get Quote |
|
| 10MG | 679 | Get Quote |
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| 25MG | 1003 | Get Quote |
|
| 50MG | 1362 | Get Quote |
|
| 100MG | 1782 | Get Quote |
|
| 500MG | 3573 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameJB062
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NoteResearch use only, not for human use.
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Brief DescriptionJB062 is a chemical compound acting as a nonmuscle myosin inhibitor, exhibiting IC50 values of 1.6, 5.4, and >100 μM against skeletal muscle myosin, cardiac muscle myosin, and smooth muscle myosin II, respectively.
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DescriptionJB062 is a nonmuscle myosin inhibitor with IC50 values of 1.6, 5.4, and >100 μM for Skeletal muscle myosin, Cardiac muscle myosin, and Smooth muscle myosin II, respectively. JB062 has cytotoxic to human cancer cells but not normal cells. JB062 can be used in research of muscle spasticity, chronic musculoskeletal pain, and hypertrophic cardiomyopathy.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCytoskeleton/Cell Adhesion Molecules
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TargetMyosin
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RecptorMyosin
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Research Area——
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Indication——
Chemical Information
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CAS Number2417988-00-0
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Formula Weight323.34
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Molecular FormulaC19H17NO4
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Purity>98% (HPLC)
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Solubility——
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SMILESOC=1C=2C(OC(=O)C1C(=NCC3=CC=C(OC)C=C3)C)=CC=CC2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Smith JD, et, al. Isoform selectivities of novel 4-hydroxycoumarin imines as inhibitors of myosin II. Eur J Med Chem. 2022 Dec 12;247:115008.?
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