Cart
sales@molnova.com
JB002
CAS No. 30408-07-2
JB002( —— )
Catalog No. M36394 CAS No. 30408-07-2
JB002, a myosin II inhibitor, exhibits potent activity with an IC50 of ≤10 μM. It holds potential for research applications in muscle spasticity, chronic musculoskeletal pain, and hypertrophic cardiomyopathy.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 106 | In Stock |
|
| 5MG | 163 | In Stock |
|
| 10MG | 264 | In Stock |
|
| 25MG | 518 | In Stock |
|
| 50MG | 723 | In Stock |
|
| 100MG | 981 | In Stock |
|
| 500MG | 1962 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameJB002
-
NoteResearch use only, not for human use.
-
Brief DescriptionJB002, a myosin II inhibitor, exhibits potent activity with an IC50 of ≤10 μM. It holds potential for research applications in muscle spasticity, chronic musculoskeletal pain, and hypertrophic cardiomyopathy.
-
DescriptionJB002 is a myosin II inhibitor, with an IC50 of ≤10 μM. JB002 can be used for the research of muscle spasticity, chronic musculoskeletal pain, and hypertrophic cardiomyopathy.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayCytoskeleton/Cell Adhesion Molecules
-
TargetMyosin
-
RecptorMyosin
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number30408-07-2
-
Formula Weight293.32
-
Molecular FormulaC18H15NO3
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 31.25 mg/mL (106.54 mM; Ultrasonic (<60°C)
-
SMILESC\C(=N/Cc1ccccc1)c1c(O)c2ccccc2oc1=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Smith JD, et, al. Isoform selectivities of novel 4-hydroxycoumarin imines as inhibitors of myosin II. Eur J Med Chem. 2022 Dec 12;247:115008. ?
molnova catalog
related products
-
Mavacamten
Mavacamten (SAR-439152, MYK-461) is a small molecule that reduces contractility by decreasing the ATPase activity of the cardiac myosin heavy chain.
-
JB002
JB002, a myosin II inhibitor, exhibits potent activity with an IC50 of ≤10 μM. It holds potential for research applications in muscle spasticity, chronic musculoskeletal pain, and hypertrophic cardiomyopathy.
-
para-Nitroblebbistat...
para-Nitroblebbistatin is a non-cytotoxic, non-fluorescent, photostable, and specific inhibitor of myosin II.
