Isovalerylshikonin
CAS No. 76549-35-4
Isovalerylshikonin ( —— )
Catalog No. M29255 CAS No. 76549-35-4
Isovalerylshikonin is a natural product from Onosma heterophylla and Arnebia euchroma.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 519 | Get Quote |
|
10MG | 743 | Get Quote |
|
100MG | Get Quote | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
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Product NameIsovalerylshikonin
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NoteResearch use only, not for human use.
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Brief DescriptionIsovalerylshikonin is a natural product from Onosma heterophylla and Arnebia euchroma.
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DescriptionIsovalerylshikonin is a natural product from Onosma heterophylla and Arnebia euchroma.(In Vitro):Isovalerylshikonin exhibited marginal antibacterial activity against drug-resistant Staphylococcus aureus RN4220, with an MIC of 16 mg/L. (In Vivo):A peritonitis/sepsis model was employed to test the in vivo synergistic activity of IVS and STM. IVS synergistically decreased the bacteria count with STM in peritoneal, spleen and liver, and increased mouse survival with STM in 7 days. The acute toxicity of IVS was tested, and the LD50 of IVS with a single exposure was 2.584 g/kg in mice. Overall, isovalerylshikonin, a low toxicity resistance-modifying agent, exhibited synergistic antibacterial activities in vitro and in vivo against drug-resistant S. aureus. The effects were mediated by suppression of msrA mRNA expression and bacterial efflux.
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Synonyms——
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PathwayGPCR/G Protein
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TargetAntibacterial
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RecptorAntibacterial
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Research Area——
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Indication——
Chemical Information
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CAS Number76549-35-4
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Formula Weight372.4
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Molecular FormulaC21H24O6
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Purity>98% (HPLC)
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Solubility——
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SMILESCC(C)CC(=O)OC(CC=C(C)C)C1=CC(=O)c2c(O)ccc(O)c2C1=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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