Isovalerylshikonin

CAS No. 76549-35-4

Isovalerylshikonin ( —— )

Catalog No. M29255 CAS No. 76549-35-4

Isovalerylshikonin is a natural product from Onosma heterophylla and Arnebia euchroma.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Isovalerylshikonin
  • Note
    Research use only, not for human use.
  • Brief Description
    Isovalerylshikonin is a natural product from Onosma heterophylla and Arnebia euchroma.
  • Description
    Isovalerylshikonin is a natural product from Onosma heterophylla and Arnebia euchroma.(In Vitro):Isovalerylshikonin exhibited marginal antibacterial activity against drug-resistant Staphylococcus aureus RN4220, with an MIC of 16 mg/L. (In Vivo):A peritonitis/sepsis model was employed to test the in vivo synergistic activity of IVS and STM. IVS synergistically decreased the bacteria count with STM in peritoneal, spleen and liver, and increased mouse survival with STM in 7 days. The acute toxicity of IVS was tested, and the LD50 of IVS with a single exposure was 2.584 g/kg in mice. Overall, isovalerylshikonin, a low toxicity resistance-modifying agent, exhibited synergistic antibacterial activities in vitro and in vivo against drug-resistant S. aureus. The effects were mediated by suppression of msrA mRNA expression and bacterial efflux.
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Antibacterial
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    76549-35-4
  • Formula Weight
    372.4
  • Molecular Formula
    C21H24O6
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC(C)CC(=O)OC(CC=C(C)C)C1=CC(=O)c2c(O)ccc(O)c2C1=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
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