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AgrA inhibitor F19
CAS No. 1532534-68-1
AgrA inhibitor F19( —— )
Catalog No. M12157 CAS No. 1532534-68-1
AgrA inhibitor F19 is a small-molecule AgrA inhibitor that act as antivirulence agent against Gram-positive pathogens.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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| 500MG | Get Quote | Get Quote |
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Biological Information
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Product NameAgrA inhibitor F19
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NoteResearch use only, not for human use.
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Brief DescriptionAgrA inhibitor F19 is a small-molecule AgrA inhibitor that act as antivirulence agent against Gram-positive pathogens.
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DescriptionAgrA inhibitor F19 is a small-molecule AgrA inhibitor that act as antivirulence agent against Gram-positive pathogens, blocks staphylococcal transcription factor AgrA from binding to its promoter and inhibits toxin and virulence factor transcription; binds to C-terminal DNA-binding domain (AgrA_C) from Staphylococcus epidermidis with an affinity of 2.7 uM, potentiates β-lactam antibiotics in a MRSA wound model.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayGPCR/G Protein
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TargetAntibacterial
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RecptorAntibacterial
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Research Area——
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Indication——
Chemical Information
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CAS Number1532534-68-1
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Formula Weight370.489
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Molecular FormulaC23H30O4
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Purity>98% (HPLC)
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Solubility——
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SMILESCCCCCCC1=CC(=C(C=C1O)O)C(=O)COC2=CC=C(C=C2)C(C)C
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Chemical Name1-(5-hexyl-2,4-dihydroxyphenyl)-2-(4-isopropylphenoxy)ethan-1-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Greenberg M, et al. Sci Rep. 2018 Oct 1;8(1):14578.
2. Khodaverdian V, et al. Antimicrob Agents Chemother. 2013 Aug;57(8):3645-52.
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