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Inh2-B1
CAS No. 690216-38-7
Inh2-B1( STK1 inhibitor B1 )
Catalog No. M15641 CAS No. 690216-38-7
Inh2-B1 (STK1 inhibitor B1) is a novel specific S aureus Ser/Thr protein kinase (STK1) inhibitor with IC50 of 49 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameInh2-B1
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NoteResearch use only, not for human use.
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Brief DescriptionInh2-B1 (STK1 inhibitor B1) is a novel specific S aureus Ser/Thr protein kinase (STK1) inhibitor with IC50 of 49 uM.
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DescriptionInh2-B1 (STK1 inhibitor B1) is a novel specific S aureus Ser/Thr protein kinase (STK1) inhibitor with IC50 of 49 uM, directly binds to ATP-binding catalytic domain; exhibits in vitro growth inhibition of MRSA, and in vivo protection in mice against the lethal MRSA challenge; down-regulates cell wall hydrolase genes and disrupts the biofilm formation of MRSA.
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In Vitro——
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In Vivo——
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SynonymsSTK1 inhibitor B1
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PathwayGPCR/G Protein
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TargetAntibacterial
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RecptorAntibacterial
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Research Area——
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Indication——
Chemical Information
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CAS Number690216-38-7
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Formula Weight411.45
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Molecular FormulaC19H13N3O4S2
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical NameMethyl 5-oxo-3-(phenyl carbamoyl)-1-thioxo-4,5dihydro[1,3]thiazolo[3,4-a]quinazoline-8-carboxylate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Kant S, et al. Sci Rep. 2017 Jul 11;7(1):5067.
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