Inh2-B1

CAS No. 690216-38-7

Inh2-B1 ( STK1 inhibitor B1 )

Catalog No. M15641 CAS No. 690216-38-7

Inh2-B1 (STK1 inhibitor B1) is a novel specific S aureus Ser/Thr protein kinase (STK1) inhibitor with IC50 of 49 uM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Inh2-B1
  • Note
    Research use only, not for human use.
  • Brief Description
    Inh2-B1 (STK1 inhibitor B1) is a novel specific S aureus Ser/Thr protein kinase (STK1) inhibitor with IC50 of 49 uM.
  • Description
    Inh2-B1 (STK1 inhibitor B1) is a novel specific S aureus Ser/Thr protein kinase (STK1) inhibitor with IC50 of 49 uM, directly binds to ATP-binding catalytic domain; exhibits in vitro growth inhibition of MRSA, and in vivo protection in mice against the lethal MRSA challenge; down-regulates cell wall hydrolase genes and disrupts the biofilm formation of MRSA.
  • Synonyms
    STK1 inhibitor B1
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Antibacterial
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    690216-38-7
  • Formula Weight
    411.45
  • Molecular Formula
    C19H13N3O4S2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    Methyl 5-oxo-3-(phenyl carbamoyl)-1-thioxo-4,5dihydro[1,3]thiazolo[3,4-a]quinazoline-8-carboxylate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kant S, et al. Sci Rep. 2017 Jul 11;7(1):5067.
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