Dup-721
CAS No. 104421-21-8
Dup-721 ( —— )
Catalog No. M28176 CAS No. 104421-21-8
DuP-721 is a broad spectrum and orally active antibacterial agent against a variety of clinically susceptible and resistant bacteria, especially M. tuberculosis.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
2MG | 69 | Get Quote |
|
5MG | 115 | Get Quote |
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10MG | 192 | Get Quote |
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25MG | 394 | Get Quote |
|
50MG | 584 | Get Quote |
|
100MG | 833 | Get Quote |
|
500MG | 1683 | Get Quote |
|
1G | Get Quote | Get Quote |
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Biological Information
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Product NameDup-721
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NoteResearch use only, not for human use.
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Brief DescriptionDuP-721 is a broad spectrum and orally active antibacterial agent against a variety of clinically susceptible and resistant bacteria, especially M. tuberculosis.
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DescriptionDuP-721 is a broad spectrum and orally active antibacterial agent against a variety of clinically susceptible and resistant bacteria, especially M. tuberculosis.(In Vitro):DuP-721 (1.5-4 μg/ml) inhibits equally the strains of Mycobacterium tuberculosis susceptible and resistant to conventional antituberculosis drug. And it does not show cross resistance to any of the anti-tuberculosis drugs tested.DuP-721 is inactive against M. avium and M. intracellulare at 250 μg/ml. It inhibits M. gordonoe and M. fortuitum at 3.9 μg/ml and M. kansassi and M. scrofulaceum at 1.95 μg/ml and 15.6 μg/ml, respectively.(In Vivo):DuP-721 (oral gavage; 50-160 mg/kg) is protective against M. tuberculosis infection in mice. DuP-721 protects 100% of the infected animals at 50 mg/kg p.o. dose when administered daily for 17 days, and the same effect is observed at 160 mg/kg dose when the drug is administered only on day 11 and 12 post infection.
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Synonyms——
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PathwayGPCR/G Protein
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TargetAntibacterial
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RecptorNuclear factor of activated Tcells (NFAT)
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Research Area——
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Indication——
Chemical Information
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CAS Number104421-21-8
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Formula Weight276.3
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Molecular FormulaC14H16N2O4
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Purity>98% (HPLC)
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Solubility——
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SMILESN/A
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Colin A Bretz,?et al. The role of the NFAT signaling pathway in retinal neovascularization. Invest Ophthalmol Vis Sci.?2013 Oct 25;54(10):7020-7.
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