Inauhzin
CAS No. 309271-94-1
Inauhzin ( Inauhzin )
Catalog No. M13988 CAS No. 309271-94-1
Inauhzin(INZ) is a novel small molecule that effectively reactivates p53 by inhibiting SIRT1 activity.
Purity : >98%(HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
2MG | 46 | In Stock |
|
5MG | 82 | In Stock |
|
10MG | 101 | In Stock |
|
25MG | 214 | In Stock |
|
50MG | 367 | In Stock |
|
100MG | 527 | In Stock |
|
500MG | 1143 | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
-
Product NameInauhzin
-
NoteResearch use only, not for human use.
-
Brief DescriptionInauhzin(INZ) is a novel small molecule that effectively reactivates p53 by inhibiting SIRT1 activity.
-
DescriptionInauhzin(INZ) is a novel small molecule that effectively reactivates p53 by inhibiting SIRT1 activity, promotes p53-dependent apoptosis of human Y cells without causing apparently genotoxic stress(IC50=3 uM, in A549 cell).
-
SynonymsInauhzin
-
PathwayChromatin/Epigenetic
-
TargetSirtuin
-
RecptorSIRT1
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number309271-94-1
-
Formula Weight469.58
-
Molecular FormulaC25H19N5OS2
-
Purity>98%(HPLC)
-
SolubilityDMSO: 10 mM
-
SMILESCCC(SC1=NN=C2C(NC3=C2C=CC=C3)=N1)C(N4C5=C(C=CC=C5)SC6=CC=CC=C46)=O
-
Chemical Name2-((5H-[1,2,4]triazino[5,6-b]indol-3-yl)thio)-1-(10H-phenothiazin-10-yl)butan-1-one
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Zhang Q, et al. EMBO Mol Med. 2012 Apr; 4(4): 298-31
molnova catalog
related products
-
N-Caffeoyltryptophan
N-Caffeoyltryptophan, a potential Sirt inhibitor, is screened using coffee extract. N-Caffeoyltryptophan inhibited Sirt2 (IC50; 8.7 μM) better than Sirt1(IC50; 34μM).
-
SRT 3025
SRT3025 is a potent, orallu actuve SIRT1 activator that activates wild-type Sirt1 protein.
-
Tenovin-1
Tenovin-1 (Tenovin1) is a small molecules that activate p53 and decreases tumor growth through inhibition of the protein-deacetylating activities of SirT1 and SirT2.