Inauhzin

CAS No. 309271-94-1

Inauhzin ( Inauhzin )

Catalog No. M13988 CAS No. 309271-94-1

Inauhzin(INZ) is a novel small molecule that effectively reactivates p53 by inhibiting SIRT1 activity.

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 46 In Stock
5MG 82 In Stock
10MG 101 In Stock
25MG 214 In Stock
50MG 367 In Stock
100MG 527 In Stock
500MG 1143 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Inauhzin
  • Note
    Research use only, not for human use.
  • Brief Description
    Inauhzin(INZ) is a novel small molecule that effectively reactivates p53 by inhibiting SIRT1 activity.
  • Description
    Inauhzin(INZ) is a novel small molecule that effectively reactivates p53 by inhibiting SIRT1 activity, promotes p53-dependent apoptosis of human Y cells without causing apparently genotoxic stress(IC50=3 uM, in A549 cell).
  • Synonyms
    Inauhzin
  • Pathway
    Chromatin/Epigenetic
  • Target
    Sirtuin
  • Recptor
    SIRT1
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    309271-94-1
  • Formula Weight
    469.58
  • Molecular Formula
    C25H19N5OS2
  • Purity
    >98%(HPLC)
  • Solubility
    DMSO: 10 mM
  • SMILES
    CCC(SC1=NN=C2C(NC3=C2C=CC=C3)=N1)C(N4C5=C(C=CC=C5)SC6=CC=CC=C46)=O
  • Chemical Name
    2-((5H-[1,2,4]triazino[5,6-b]indol-3-yl)thio)-1-(10H-phenothiazin-10-yl)butan-1-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Zhang Q, et al. EMBO Mol Med. 2012 Apr; 4(4): 298-31
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