N-Caffeoyltryptophan

CAS No. 109163-69-1

N-Caffeoyltryptophan( trans-Caffeoyl-L-tryptophan )

Catalog No. M29476 CAS No. 109163-69-1

N-Caffeoyltryptophan, a potential Sirt inhibitor, is screened using coffee extract. N-Caffeoyltryptophan inhibited Sirt2 (IC50; 8.7 μM) better than Sirt1(IC50; 34μM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 447 Get Quote
25MG 714 Get Quote
50MG 1017 Get Quote
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Biological Information

  • Product Name
    N-Caffeoyltryptophan
  • Note
    Research use only, not for human use.
  • Brief Description
    N-Caffeoyltryptophan, a potential Sirt inhibitor, is screened using coffee extract. N-Caffeoyltryptophan inhibited Sirt2 (IC50; 8.7 μM) better than Sirt1(IC50; 34μM).
  • Description
    N-Caffeoyltryptophan, a potential Sirt inhibitor, is screened using coffee extract. N-Caffeoyltryptophan inhibited Sirt2 (IC50; 8.7 μM) better than Sirt1(IC50; 34μM).(In Vitro):In cellular levels,N-Caffeoyltryptophan was able to increase the acetylation of total lysine, cortactin and histone H3 in neuronal NG108-15 cells. In the same cells, the amide also increased the acetylation of lysine (K382) in p53, but not (K305).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    trans-Caffeoyl-L-tryptophan
  • Pathway
    Chromatin/Epigenetic
  • Target
    Sirtuin
  • Recptor
    Sirtuin
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    109163-69-1
  • Formula Weight
    366.373
  • Molecular Formula
    C20H18N2O5
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    OC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)\C=C\c1ccc(O)c(O)c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
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