Sirt2-IN-1
CAS No. 1862238-00-3
Sirt2-IN-1 ( —— )
Catalog No. M26448 CAS No. 1862238-00-3
Sirt2-IN-1 is a inhibitor of sirtuin 2 (Sirt2)(IC50 of 163 nM).
Purity : >98% (HPLC)
Size | Price / USD | Stock | Quantity |
5MG | 340 | Get Quote |
|
10MG | 537 | Get Quote |
|
25MG | 858 | Get Quote |
|
50MG | 1161 | Get Quote |
|
100MG | 1557 | Get Quote |
|
500MG | 3141 | Get Quote |
|
1G | Get Quote | Get Quote |
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Biological Information
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Product NameSirt2-IN-1
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NoteResearch use only, not for human use.
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Brief DescriptionSirt2-IN-1 is a inhibitor of sirtuin 2 (Sirt2)(IC50 of 163 nM).
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DescriptionSirt2-IN-1 is a inhibitor of sirtuin 2 (Sirt2)(IC50 of 163 nM).
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Synonyms——
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PathwayChromatin/Epigenetic
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TargetSirtuin
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Recptornorepinephrine reuptake; serotonin reuptake
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Research Area——
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Indication——
Chemical Information
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CAS Number1862238-00-3
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Formula Weight557.7
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Molecular FormulaC28H27N7O2S2
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Purity>98% (HPLC)
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Solubility——
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SMILESCc1cc(C)nc(SCC(=O)Nc2ncc(Cc3cccc(OCc4cn(Cc5ccccc5)nn4)c3)s2)n1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Pristimerin
Pristimerin has anticancer activity, treatment with Pristimerin may be a potential strategy for the suppression of hypoxia-induced metastasis through the reversal of hypoxia-induced stem cell characteristics and EMT in cancer cells.
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RK-9123016
RK-9123016 is a SIRT2 inhibitor. RK-9123016 increases the acetylation level of eukaryotic translation initiation factor 5A (eIF5A), a physiological substrate of SIRT2, and reduces cell viability of human breast cancer cells accompanied with a decrease in c-Myc expression.
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Alogliptin
Alogliptin(SYR-322) is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10, 000-fold selectivity over DPP-8 and DPP-9.