Cart
sales@molnova.com
Idarubicin
CAS No. 58957-92-9
Idarubicin ( 4-Demethoxydaunorubicin;IMI-30;NSC 256439 )
Catalog No. M15179 CAS No. 58957-92-9
Idarubicin (4-Demethoxydaunorubicin;IMI-30;NSC 256439) is an anthracycline antileukemic that inserts into DNA and prevents DNA unwinding by interfering with the enzyme Topoisomerase II in cancer cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameIdarubicin
-
NoteResearch use only, not for human use.
-
Brief DescriptionIdarubicin (4-Demethoxydaunorubicin;IMI-30;NSC 256439) is an anthracycline antileukemic that inserts into DNA and prevents DNA unwinding by interfering with the enzyme Topoisomerase II in cancer cells.
-
DescriptionIdarubicin (4-Demethoxydaunorubicin;IMI-30;NSC 256439) is an anthracycline antileukemic that inserts into DNA and prevents DNA unwinding by interfering with the enzyme Topoisomerase II in cancer cells; inhibits the proliferation of MCF-7 cells with IC50 of 0.1 uM; also induces histone eviction from chromatin.Chemotherapeutic Agents Approved
-
Synonyms4-Demethoxydaunorubicin;IMI-30;NSC 256439
-
PathwayCell Cycle/DNA Damage
-
TargetTopoisomerase
-
RecptorTopoisomerase
-
Research AreaCancer
-
IndicationChemotherapeutic
Chemical Information
-
CAS Number58957-92-9
-
Formula Weight497.49
-
Molecular FormulaC26H27NO9
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCC1C(C(CC(O1)OC2CC(CC3=C2C(=C4C(=C3O)C(=O)C5=CC=CC=C5C4=O)O)(C(=O)C)O)N)O
-
Chemical Name(7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-8,10-dihydro-7H-tetracene-5,12-dione
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Gewirtz DA, et al. Cancer Chemother Pharmacol. 1998;41(5):361-9.
2. Pang B, et al. Nat Commun. 2013;4:1908.
3. Nitiss JL. Nat Rev Cancer. 2009 May;9(5):338-50.
2. Pang B, et al. Nat Commun. 2013;4:1908.
3. Nitiss JL. Nat Rev Cancer. 2009 May;9(5):338-50.
molnova catalog
related products
-
Doxorubicin hydrochl...
Doxorubicin (Adriamycin) is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis.
-
Nalidixic acid sodiu...
A synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum.
-
Idarubicin
Idarubicin (4-Demethoxydaunorubicin;IMI-30;NSC 256439) is an anthracycline antileukemic that inserts into DNA and prevents DNA unwinding by interfering with the enzyme Topoisomerase II in cancer cells.
