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Home - Products - Cell Cycle/DNA Damage - Topoisomerase - 9-Aminocamptothecin

9-Aminocamptothecin

CAS No. 91421-43-1

9-Aminocamptothecin ( 9-amino-CPT;9-amino-2(S)-camptothecin;Aminocamptothecin )

Catalog No. M21471 CAS No. 91421-43-1

9-Aminocamptothecin is an inhibitor of topoisomerase I with potent anticancer activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 132 Get Quote
25MG 237 Get Quote
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Biological Information

  • Product Name
    9-Aminocamptothecin
  • Note
    Research use only not for human use.
  • Brief Description
    9-Aminocamptothecin is an inhibitor of topoisomerase I with potent anticancer activity.
  • Description
    9-Aminocamptothecin is an inhibitor of topoisomerase I with potent anticancer activity.
  • Synonyms
    9-amino-CPT;9-amino-2(S)-camptothecin;Aminocamptothecin
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    Topoisomerase
  • Recptor
    Topo I
  • Research Area
    cancer
  • Indication
    Ovarian Neoplasms

Chemical Information

  • CAS Number
    91421-43-1
  • Formula Weight
    363.4
  • Molecular Formula
    C20H17N3O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:3.33 mg/mL (9.16 mM)
  • SMILES
    CC[C@](C(C=C(c1nc2ccc3)N4Cc1cc2c3N)=C(CO1)C4=O)(C1=O)O
  • Chemical Name
    (S)-10-amino-4-ethyl-4-hydroxy-1H-pyrano[3'4':67]indolizino[12-b]quinoline-314(4H12H)-dione

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.de Souza PL et al. 9-Aminocamptothecin: a topoisomerase I inhibitor with preclinical activity in prostate cancer. Clin Cancer Res. 1997 Feb;3(2):287-94.
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